Orexin B × 10 Vials

Orexin-B, also known as Hypocretin-2, is a neuropeptide derived from the precursor protein prepro-orexin (HCRT). It belongs to the orexin/hypocretin peptide family, which has been studied in relation to neuronal signaling processes associated with arousal regulation, energy homeostasis, and neuroendocrine signaling in preclinical and experimental models. Orexin peptides are synthesized primarily in specialized neuronal populations within the hypothalamus and participate in complex neural signaling networks.

In investigational research, Orexin-B is frequently studied to examine orexin receptor signaling mechanisms, neuropeptide-mediated neurotransmission, and hypothalamic regulatory pathways. The peptide interacts with orexin receptor type 2 (OX2R), a G-protein-coupled receptor (GPCR) involved in intracellular signaling cascades associated with neuronal activation and synaptic communication.

Molecular Formula: C126H212N44O35S
Molecular Weight: 2899.36 g/mol
Synonyms: [D-Ala22]orexin-B, [Ala11,D-Leu15]-Orexin B, [D-Leu7]orexin-B
Sequence: His-Asp-Ala-Ala-Gly-Ile-Leu-Thr-Leu-NH2
Purity: ≥99%